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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: NOLC1 All Species: 23.03
Human Site: S221 Identified Species: 38.97
UniProt: Q14978 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q14978 NP_004732.2 699 73603 S221 A A S S S S S S S S S S S S D
Chimpanzee Pan troglodytes XP_001171017 700 73581 S222 A S S S S S S S S S S S S S D
Rhesus Macaque Macaca mulatta XP_001112196 701 73703 S222 K A A S S S S S S S S S S S D
Dog Lupus familis XP_851848 704 74723 S225 A A R S K S S S S S S S S D D
Cat Felis silvestris
Mouse Mus musculus O08784 1320 134983 A545 S E E E A A P A A S A A Q A K
Rat Rattus norvegicus P41777 704 73545 S231 A G S S S S S S S S S S S D D
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001511079 669 69188 A174 P G A A T K A A P K L T N G K
Chicken Gallus gallus XP_421630 694 72200 S204 A P S S S S S S S S S S E D S
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_689627 1001 102013 S305 K A A A K N D S S S S D S S D
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_730693 686 70584 V181 E E P A K P A V K A T T T K V
Honey Bee Apis mellifera XP_001120943 685 75016 A189 E S K T N I T A K T N T K S I
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_796224 791 84162 K238 A A N S K V R K A V K V T P V
Poplar Tree Populus trichocarpa
Maize Zea mays NP_001168628 517 55362 Q57 S R T L V A L Q S E A G L E A
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae P32583 406 40997
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.5 94.2 81.5 N.A. 24.9 74.1 N.A. 50.7 43.6 N.A. 36.6 N.A. 27.3 22 N.A. 34.5
Protein Similarity: 100 98.8 95.5 85.6 N.A. 36.7 81.2 N.A. 60.3 57.5 N.A. 47.5 N.A. 42.3 42.9 N.A. 47.9
P-Site Identity: 100 93.3 86.6 80 N.A. 6.6 86.6 N.A. 0 73.3 N.A. 53.3 N.A. 0 6.6 N.A. 20
P-Site Similarity: 100 100 93.3 80 N.A. 60 86.6 N.A. 46.6 73.3 N.A. 73.3 N.A. 40 60 N.A. 40
Percent
Protein Identity: N.A. 23.6 N.A. N.A. 25.1 N.A.
Protein Similarity: N.A. 40.9 N.A. N.A. 39.4 N.A.
P-Site Identity: N.A. 6.6 N.A. N.A. 0 N.A.
P-Site Similarity: N.A. 33.3 N.A. N.A. 0 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 43 36 22 22 8 15 15 22 15 8 15 8 0 8 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 8 0 0 0 0 8 0 22 43 % D
% Glu: 15 15 8 8 0 0 0 0 0 8 0 0 8 8 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 0 0 0 0 0 0 0 0 8 0 8 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 0 0 0 0 0 0 8 % I
% Lys: 15 0 8 0 29 8 0 8 15 8 8 0 8 8 15 % K
% Leu: 0 0 0 8 0 0 8 0 0 0 8 0 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 8 0 8 8 0 0 0 0 8 0 8 0 0 % N
% Pro: 8 8 8 0 0 8 8 0 8 0 0 0 0 8 0 % P
% Gln: 0 0 0 0 0 0 0 8 0 0 0 0 8 0 0 % Q
% Arg: 0 8 8 0 0 0 8 0 0 0 0 0 0 0 0 % R
% Ser: 15 15 29 50 36 43 43 50 58 58 50 43 43 36 8 % S
% Thr: 0 0 8 8 8 0 8 0 0 8 8 22 15 0 0 % T
% Val: 0 0 0 0 8 8 0 8 0 8 0 8 0 0 15 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _